Blasphemy. Once tableted, you will never live without it!
Anyway, you'll get used to it, in a months time or so. To get yurself quickly started, limit the drawing area of the tablet (since you got a nice big one) in the tablet controls first so you can familiarise yourself with pressure control first. Afterwards you can go size up. I remember using an 8x11 one at a place I used to work... dang was it tiring! Scaling down the drawing area helped a lot (less distance you have to move your hand, at the cost of less precision).